Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 11056.147 | 1.0297 | 1.0211 | 2.7832 | |
| MCF 10A | NM | Basal B | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 11056.147 | 1.0318 | 1.0227 | 2.7832 | |
| MCF 10A | NM | Basal B | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 11056.147 | 1.0962 | 1.0671 | 2.7832 | |
| MCF 10A | NM | Basal B | Oxamflatin | HDAC | HDAC | 0.107 | uM | 11056.147 | 0.9217 | 0.9423 | 2.7832 | |
| MCF 10A | NM | Basal B | Oxamflatin | HDAC | HDAC | 0.533 | uM | 11056.147 | 0.6692 | 0.7312 | 2.7832 | |
| MCF 10A | NM | Basal B | Oxamflatin | HDAC | HDAC | 2.67 | uM | 11056.147 | 0.1305 | -0.0378 | 2.7832 | |
| MCF 10A | NM | Basal B | Oxamflatin | HDAC | HDAC | 13.3 | uM | 11056.147 | 0.0083 | -0.6426 | 2.7832 | |
| MCF 10A | NM | Basal B | Oxamflatin | HDAC | HDAC | 66.7 | uM | 11056.147 | 0.0063 | -0.6755 | 2.7832 | |
| MCF 10F | NM | - | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 12254.147 | 1.0459 | 1.0636 | 1.4316 | |
| MCF 10F | NM | - | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 12254.147 | 1.0208 | 1.0290 | 1.4316 | |
| MCF 10F | NM | - | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 12254.147 | 1.0770 | 1.1064 | 1.4316 | |
| MCF 10F | NM | - | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 12254.147 | 1.0586 | 1.0811 | 1.4316 | |
| MCF 10F | NM | - | Oxamflatin | HDAC | HDAC | 0.107 | uM | 12254.147 | 1.0054 | 1.0076 | 1.4316 | |
| MCF 10F | NM | - | Oxamflatin | HDAC | HDAC | 0.533 | uM | 12254.147 | 1.0978 | 1.1347 | 1.4316 | |
| MCF 10F | NM | - | Oxamflatin | HDAC | HDAC | 2.67 | uM | 12254.147 | 0.8110 | 0.7278 | 1.4316 | |
| MCF 10F | NM | - | Oxamflatin | HDAC | HDAC | 13.3 | uM | 12254.147 | 0.0824 | -0.6502 | 1.4316 | |
| MCF 10F | NM | - | Oxamflatin | HDAC | HDAC | 66.7 | uM | 12254.147 | 0.0170 | -0.8841 | 1.4316 | |
| MCF12A | NM | Basal B | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 10817.147 | 0.9753 | 0.9670 | 1.5041 | |
| MCF12A | NM | Basal B | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 10817.147 | 0.9708 | 0.9610 | 1.5041 | |
| MCF12A | NM | Basal B | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 10817.147 | 1.0269 | 1.0356 | 1.5041 | |
| MCF12A | NM | Basal B | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 10817.147 | 1.0219 | 1.0290 | 1.5041 | |
| MCF12A | NM | Basal B | Oxamflatin | HDAC | HDAC | 0.107 | uM | 10817.147 | 0.9951 | 0.9935 | 1.5041 | |
| MCF12A | NM | Basal B | Oxamflatin | HDAC | HDAC | 0.533 | uM | 10817.147 | 0.9383 | 0.9171 | 1.5041 | |
| MCF12A | NM | Basal B | Oxamflatin | HDAC | HDAC | 2.67 | uM | 10817.147 | 0.5475 | 0.3400 | 1.5041 | |
| MCF12A | NM | Basal B | Oxamflatin | HDAC | HDAC | 13.3 | uM | 10817.147 | 0.0179 | -0.8623 | 1.5041 |