Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MB 157	Unknown	Unknown	Nutlin 3a	MDM2	MDM2	0.00427	uM	7482.066	1.0489	1.0859	1.1347
MB 157	Unknown	Unknown	Nutlin 3a	MDM2	MDM2	0.0213	uM	7482.066	1.0033	1.0058	1.1347
MB 157	Unknown	Unknown	Nutlin 3a	MDM2	MDM2	0.107	uM	7482.066	1.1293	1.2263	1.1347
MB 157	Unknown	Unknown	Nutlin 3a	MDM2	MDM2	0.533	uM	7482.066	1.0265	1.0466	1.1347
MB 157	Unknown	Unknown	Nutlin 3a	MDM2	MDM2	2.67	uM	7482.066	1.3216	1.5571	1.1347
MB 157	Unknown	Unknown	Nutlin 3a	MDM2	MDM2	13.3	uM	7482.066	0.9241	0.8655	1.1347
MB 157	Unknown	Unknown	Nutlin 3a	MDM2	MDM2	66.7	uM	7482.066	0.4341	-0.0414	1.1347
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	0.000171	uM	7483.066	0.9352	0.9594	3.2636
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	0.000853	uM	7483.066	1.0003	1.0002	3.2636
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	0.00427	uM	7483.066	0.9441	0.9650	3.2636
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	0.0213	uM	7483.066	0.9392	0.9619	3.2636
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	0.107	uM	7483.066	0.9987	0.9992	3.2636
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	0.533	uM	7483.066	0.8901	0.9299	3.2636
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	2.67	uM	7483.066	0.7233	0.8110	3.2636
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	13.3	uM	7483.066	0.3753	0.4812	3.2636
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	66.7	uM	7483.066	0.2353	0.2838	3.2636
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	0.000171	uM	7484.066	0.8842	0.9149	2.8312
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	0.000853	uM	7484.066	0.9675	0.9768	2.8312
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	0.00427	uM	7484.066	0.9026	0.9289	2.8312
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	0.0213	uM	7484.066	0.9238	0.9448	2.8312
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	0.107	uM	7484.066	0.9287	0.9484	2.8312
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	0.533	uM	7484.066	0.7658	0.8201	2.8312
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	2.67	uM	7484.066	0.5820	0.6520	2.8312
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	13.3	uM	7484.066	0.3774	0.4176	2.8312
MCF 10A	NM	Basal B	Nutlin 3a	MDM2	MDM2	66.7	uM	7484.066	0.0179	-0.5168	2.8312

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)