Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 10093.021 | 0.8119 | 0.5936 | 0.9172 | |
| MDA-MB-157 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 10093.021 | 0.7183 | 0.3943 | 0.9172 | |
| MDA-MB-157 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 10093.021 | 0.8965 | 0.7753 | 0.9172 | |
| MDA-MB-157 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 10093.021 | 0.8580 | 0.6924 | 0.9172 | |
| MDA-MB-157 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 10093.021 | 0.7086 | 0.3738 | 0.9172 | |
| MDA-MB-157 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 10093.021 | 0.5574 | 0.0576 | 0.9172 | |
| MDA-MB-157 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 10093.021 | 0.6814 | 0.3164 | 0.9172 | |
| MDA-MB-157 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 10093.021 | 0.1347 | -0.7752 | 0.9172 | |
| MDA-MB-157 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 10093.021 | 0.0088 | -0.9885 | 0.9172 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7885.011 | 1.0119 | 1.0470 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7885.011 | 1.0012 | 1.0048 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7885.011 | 1.0388 | 1.1549 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7885.011 | 0.9252 | 0.7174 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7885.011 | 0.9311 | 0.7387 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7885.011 | 0.8134 | 0.3341 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7885.011 | 0.5496 | -0.3814 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7885.011 | 0.1848 | -0.9270 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7885.011 | 0.0286 | -0.9981 | 0.5102 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7886.011 | 0.9895 | 0.9697 | 0.6942 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7886.011 | 0.9687 | 0.9104 | 0.6942 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7886.011 | 1.0203 | 1.0586 | 0.6942 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7886.011 | 0.9593 | 0.8838 | 0.6942 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7886.011 | 0.9160 | 0.7626 | 0.6942 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7886.011 | 0.7900 | 0.4241 | 0.6942 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7886.011 | 0.5117 | -0.2383 | 0.6942 |