Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7886.011 | 0.1856 | -0.8233 | 0.6942 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7886.011 | 0.0195 | -0.9931 | 0.6942 | |
| MDA-MB-231 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7892.011 | 1.0121 | 1.0092 | 2.6182 | |
| MDA-MB-231 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7892.011 | 1.0054 | 1.0041 | 2.6182 | |
| MDA-MB-231 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7892.011 | 1.0034 | 1.0026 | 2.6182 | |
| MDA-MB-231 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7892.011 | 1.0277 | 1.0210 | 2.6182 | |
| MDA-MB-231 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7892.011 | 0.9751 | 0.9808 | 2.6182 | |
| MDA-MB-231 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7892.011 | 0.7504 | 0.7922 | 2.6182 | |
| MDA-MB-231 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7892.011 | 0.5819 | 0.6264 | 2.6182 | |
| MDA-MB-231 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7892.011 | 0.3812 | 0.3837 | 2.6182 | |
| MDA-MB-231 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7892.011 | 0.0979 | -0.1767 | 2.6182 | |
| MDA-MB-361 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7896.011 | 0.9836 | 0.9699 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7896.011 | 0.9567 | 0.9205 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7896.011 | 0.9450 | 0.8989 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7896.011 | 0.8891 | 0.7957 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7896.011 | 0.8462 | 0.7161 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7896.011 | 0.6452 | 0.3383 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7896.011 | 0.5480 | 0.1521 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7896.011 | 0.1442 | -0.6613 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7896.011 | 0.0739 | -0.8165 | 1.0906 | |
| MDA-MB-361 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9648.011 | 1.0671 | 1.1968 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9648.011 | 0.9418 | 0.8340 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9648.011 | 0.9604 | 0.8866 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9648.011 | 0.9498 | 0.8565 | 0.6920 | |
| MDA-MB-361 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9648.011 | 0.8975 | 0.7105 | 0.6920 |