Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 12291.155 | 0.9725 | 0.8808 | 0.4532 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 12291.155 | 0.9725 | 0.8808 | 0.4532 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 12291.155 | 1.0671 | 1.3080 | 0.4532 | |
| BT-474 | HER2amp | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 12291.155 | 1.0671 | 1.3080 | 0.4532 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000171 | uM | 10696.146 | 0.9479 | 0.7975 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000171 | uM | 10696.146 | 0.9479 | 0.7975 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000853 | uM | 10696.146 | 0.9319 | 0.7372 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000853 | uM | 10696.146 | 0.9319 | 0.7372 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00427 | uM | 10696.146 | 0.9488 | 0.8009 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00427 | uM | 10696.146 | 0.9488 | 0.8009 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0213 | uM | 10696.146 | 1.0056 | 1.0224 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0213 | uM | 10696.146 | 1.0056 | 1.0224 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.107 | uM | 10696.146 | 0.9973 | 0.9891 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.107 | uM | 10696.146 | 0.9973 | 0.9891 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.533 | uM | 10696.146 | 1.0120 | 1.0480 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.533 | uM | 10696.146 | 1.0120 | 1.0480 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 2.67 | uM | 10696.146 | 0.9641 | 0.8593 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 2.67 | uM | 10696.146 | 0.9641 | 0.8593 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 13.3 | uM | 10696.146 | 0.9172 | 0.6829 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 13.3 | uM | 10696.146 | 0.9172 | 0.6829 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 66.7 | uM | 10696.146 | 0.9217 | 0.6995 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 66.7 | uM | 10696.146 | 0.9217 | 0.6995 | 0.5009 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 11855.155 | 0.8674 | 0.6695 | 0.7873 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 11855.155 | 0.8674 | 0.6695 | 0.7873 | |
| BT-483 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 11855.155 | 0.8266 | 0.5703 | 0.7873 |