Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 167 | uM | 10875.152 | 0.0086 | -0.9966 | 0.7465 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12428.152 | 0.9693 | 0.9297 | 0.8719 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12428.152 | 0.9343 | 0.8501 | 0.8719 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12428.152 | 0.9405 | 0.8640 | 0.8719 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12428.152 | 0.9660 | 0.9221 | 0.8719 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12428.152 | 0.9634 | 0.9163 | 0.8719 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12428.152 | 0.6928 | 0.3128 | 0.8719 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12428.152 | 0.0204 | -0.9769 | 0.8719 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12428.152 | 0.0179 | -0.9802 | 0.8719 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 167 | uM | 12428.152 | 0.0179 | -0.9802 | 0.8719 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10819.152 | 1.0850 | 1.0828 | 2.0116 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10819.152 | 0.9773 | 0.9773 | 2.0116 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10819.152 | 1.0618 | 1.0605 | 2.0116 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10819.152 | 1.0148 | 1.0146 | 2.0116 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10819.152 | 1.0291 | 1.0287 | 2.0116 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10819.152 | 0.8147 | 0.8063 | 2.0116 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10819.152 | 0.0575 | -0.5164 | 2.0116 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10819.152 | 0.0075 | -0.8245 | 2.0116 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 167 | uM | 10819.152 | 0.0041 | -0.8698 | 2.0116 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 11937.159 | 1.0434 | 1.0386 | 2.2200 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 11937.159 | 0.9853 | 0.9867 | 2.2200 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 11937.159 | 1.0226 | 1.0202 | 2.2200 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 11937.159 | 1.0274 | 1.0245 | 2.2200 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.267 | uM | 11937.159 | 1.0246 | 1.0220 | 2.2200 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 1.33 | uM | 11937.159 | 0.7760 | 0.7841 | 2.2200 |