Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 11852.147 | 0.7769 | 0.6955 | 1.5284 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 11852.147 | 0.3914 | 0.0826 | 1.5284 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 11852.147 | 0.3469 | 0.0004 | 1.5284 | |
| T47D | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 10939.147 | 0.9440 | 0.9341 | 1.7195 | |
| T47D | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 10939.147 | 0.9592 | 0.9522 | 1.7195 | |
| T47D | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 10939.147 | 1.0254 | 1.0294 | 1.7195 | |
| T47D | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 10939.147 | 1.0448 | 1.0516 | 1.7195 | |
| T47D | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 10939.147 | 0.9296 | 0.9169 | 1.7195 | |
| T47D | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 10939.147 | 0.9799 | 0.9765 | 1.7195 | |
| T47D | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 10939.147 | 0.7467 | 0.6876 | 1.7195 | |
| T47D | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 10939.147 | 0.4325 | 0.2284 | 1.7195 | |
| T47D | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 10939.147 | 0.4838 | 0.3112 | 1.7195 | |
| T47DKBLUC | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 12608.147 | 0.9568 | 0.9332 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 12608.147 | 0.9102 | 0.8604 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 12608.147 | 0.9816 | 0.9717 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 12608.147 | 0.9487 | 0.9206 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12608.147 | 0.9693 | 0.9527 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12608.147 | 0.9129 | 0.8648 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12608.147 | 0.9218 | 0.8787 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12608.147 | 0.5344 | 0.2356 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 133 | uM | 12608.147 | 0.5408 | 0.2469 | 1.3009 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 10754.147 | 0.9991 | 0.9986 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 10754.147 | 0.9499 | 0.9212 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 10754.147 | 0.9423 | 0.9092 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 10754.147 | 1.0040 | 1.0063 | 1.2793 |