Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 10754.147 | 0.9996 | 0.9993 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 10754.147 | 1.0264 | 1.0411 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 10754.147 | 0.8985 | 0.8394 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 10754.147 | 0.4127 | 0.0013 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 10754.147 | 0.4838 | 0.1338 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 11938.147 | 0.9526 | 0.8614 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 11938.147 | 0.8380 | 0.5401 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 11938.147 | 0.9543 | 0.8664 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 11938.147 | 0.8880 | 0.6780 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 11938.147 | 0.9683 | 0.9069 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 11938.147 | 0.9577 | 0.8762 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 11938.147 | 0.8494 | 0.5713 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 11938.147 | 0.0247 | -0.9916 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 11938.147 | 0.0126 | -0.9969 | 0.6765 | |
| ZR-75-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 11660.147 | 0.9397 | 0.8858 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 11660.147 | 0.8974 | 0.8056 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 11660.147 | 0.9513 | 0.9078 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 11660.147 | 0.9469 | 0.8995 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 11660.147 | 0.9544 | 0.9137 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 11660.147 | 0.8901 | 0.7919 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 11660.147 | 0.9335 | 0.8741 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 11660.147 | 0.3019 | -0.3544 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 11660.147 | 0.4072 | -0.1437 | 1.0592 | |
| ZR-75-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 12003.147 | 0.9388 | 0.8965 | 1.1884 | |
| ZR-75-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 12003.147 | 0.9605 | 0.9332 | 1.1884 |