Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
ZR75B	HR+	Luminal	Oxamflatin	HDAC	HDAC	0.00427	uM	11939.147	0.9333	0.9161	1.6102
ZR75B	HR+	Luminal	Oxamflatin	HDAC	HDAC	0.0213	uM	11939.147	0.8868	0.8562	1.6102
ZR75B	HR+	Luminal	Oxamflatin	HDAC	HDAC	0.107	uM	11939.147	0.8362	0.7897	1.6102
ZR75B	HR+	Luminal	Oxamflatin	HDAC	HDAC	0.533	uM	11939.147	0.6137	0.4769	1.6102
ZR75B	HR+	Luminal	Oxamflatin	HDAC	HDAC	2.67	uM	11939.147	0.2619	-0.1296	1.6102
ZR75B	HR+	Luminal	Oxamflatin	HDAC	HDAC	13.3	uM	11939.147	0.0392	-0.7324	1.6102
ZR75B	HR+	Luminal	Oxamflatin	HDAC	HDAC	66.7	uM	11939.147	0.0123	-0.8695	1.6102
184A1	NM	Basal	PD 98059	MEK	MAPK	0.000128	uM	12509.152	0.9291	0.8959	1.3755
184A1	NM	Basal	PD 98059	MEK	MAPK	0.00064	uM	12509.152	0.9407	0.9130	1.3755
184A1	NM	Basal	PD 98059	MEK	MAPK	0.0032	uM	12509.152	1.0126	1.0184	1.3755
184A1	NM	Basal	PD 98059	MEK	MAPK	0.016	uM	12509.152	1.0046	1.0067	1.3755
184A1	NM	Basal	PD 98059	MEK	MAPK	0.08	uM	12509.152	0.9478	0.9235	1.3755
184A1	NM	Basal	PD 98059	MEK	MAPK	0.4	uM	12509.152	0.9773	0.9669	1.3755
184A1	NM	Basal	PD 98059	MEK	MAPK	2	uM	12509.152	0.9592	0.9404	1.3755
184A1	NM	Basal	PD 98059	MEK	MAPK	10	uM	12509.152	0.9494	0.9259	1.3755
184A1	NM	Basal	PD 98059	MEK	MAPK	50	uM	12509.152	0.8402	0.7622	1.3755
184B5	NM	Basal	PD 98059	MEK	MAPK	0.000128	uM	12566.152	0.9512	0.9336	1.4827
184B5	NM	Basal	PD 98059	MEK	MAPK	0.00064	uM	12566.152	1.0101	1.0135	1.4827
184B5	NM	Basal	PD 98059	MEK	MAPK	0.0032	uM	12566.152	0.9660	0.9539	1.4827
184B5	NM	Basal	PD 98059	MEK	MAPK	0.016	uM	12566.152	0.9999	0.9999	1.4827
184B5	NM	Basal	PD 98059	MEK	MAPK	0.08	uM	12566.152	1.0218	1.0293	1.4827
184B5	NM	Basal	PD 98059	MEK	MAPK	0.4	uM	12566.152	0.9866	0.9818	1.4827
184B5	NM	Basal	PD 98059	MEK	MAPK	2	uM	12566.152	1.0233	1.0314	1.4827
184B5	NM	Basal	PD 98059	MEK	MAPK	10	uM	12566.152	1.0130	1.0175	1.4827
184B5	NM	Basal	PD 98059	MEK	MAPK	50	uM	12566.152	0.9317	0.9069	1.4827

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)