Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM225CWN | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 133 | uM | 12098.147 | 0.3369 | -0.1980 | 1.1904 | |
| SUM229PE | TNBC | - | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 11058.147 | 0.9841 | 0.9848 | 2.1077 | |
| SUM229PE | TNBC | - | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 11058.147 | 0.9206 | 0.9230 | 2.1077 | |
| SUM229PE | TNBC | - | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 11058.147 | 1.0171 | 1.0161 | 2.1077 | |
| SUM229PE | TNBC | - | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 11058.147 | 0.9952 | 0.9954 | 2.1077 | |
| SUM229PE | TNBC | - | Olomoucine II | CDK1 | CDK | 0.213 | uM | 11058.147 | 1.0265 | 1.0250 | 2.1077 | |
| SUM229PE | TNBC | - | Olomoucine II | CDK1 | CDK | 1.07 | uM | 11058.147 | 0.9838 | 0.9845 | 2.1077 | |
| SUM229PE | TNBC | - | Olomoucine II | CDK1 | CDK | 5.33 | uM | 11058.147 | 0.7859 | 0.7840 | 2.1077 | |
| SUM229PE | TNBC | - | Olomoucine II | CDK1 | CDK | 26.7 | uM | 11058.147 | 0.2746 | 0.0832 | 2.1077 | |
| SUM229PE | TNBC | - | Olomoucine II | CDK1 | CDK | 133 | uM | 11058.147 | 0.2550 | 0.0459 | 2.1077 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 10695.147 | 1.0144 | 1.0190 | 1.5141 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 10695.147 | 1.0002 | 1.0002 | 1.5141 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 10695.147 | 0.9715 | 0.9622 | 1.5141 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 10695.147 | 1.0383 | 1.0502 | 1.5141 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 10695.147 | 1.0381 | 1.0500 | 1.5141 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 10695.147 | 0.8112 | 0.7419 | 1.5141 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 10695.147 | 0.7164 | 0.6047 | 1.5141 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 10695.147 | 0.3119 | -0.0735 | 1.5141 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 10695.147 | 0.3077 | -0.0819 | 1.5141 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 11852.147 | 0.9620 | 0.9500 | 1.5284 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 11852.147 | 0.9813 | 0.9755 | 1.5284 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 11852.147 | 0.9894 | 0.9861 | 1.5284 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 11852.147 | 0.9868 | 0.9826 | 1.5284 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 11852.147 | 0.9594 | 0.9465 | 1.5284 | |
| SUM52PE | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 11852.147 | 0.8921 | 0.8560 | 1.5284 |