Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MB 157 | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 12580.147 | 1.0256 | 1.0227 | 2.2358 | |
| MB 157 | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 12580.147 | 1.0426 | 1.0377 | 2.2358 | |
| MB 157 | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 12580.147 | 1.0216 | 1.0192 | 2.2358 | |
| MB 157 | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12580.147 | 1.0391 | 1.0346 | 2.2358 | |
| MB 157 | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12580.147 | 0.9932 | 0.9939 | 2.2358 | |
| MB 157 | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12580.147 | 0.7428 | 0.7509 | 2.2358 | |
| MB 157 | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12580.147 | 0.1983 | -0.0300 | 2.2358 | |
| MB 157 | Unknown | Unknown | Olomoucine II | CDK1 | CDK | 133 | uM | 12580.147 | 0.2107 | -0.0033 | 2.2358 | |
| MCF 10A | NM | Basal B | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 11056.147 | 1.0333 | 1.0237 | 2.7832 | |
| MCF 10A | NM | Basal B | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 11056.147 | 1.0564 | 1.0398 | 2.7832 | |
| MCF 10A | NM | Basal B | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 11056.147 | 1.0391 | 1.0277 | 2.7832 | |
| MCF 10A | NM | Basal B | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 11056.147 | 1.1026 | 1.0715 | 2.7832 | |
| MCF 10A | NM | Basal B | Olomoucine II | CDK1 | CDK | 0.213 | uM | 11056.147 | 1.0723 | 1.0508 | 2.7832 | |
| MCF 10A | NM | Basal B | Olomoucine II | CDK1 | CDK | 1.07 | uM | 11056.147 | 0.9625 | 0.9727 | 2.7832 | |
| MCF 10A | NM | Basal B | Olomoucine II | CDK1 | CDK | 5.33 | uM | 11056.147 | 0.1936 | 0.1087 | 2.7832 | |
| MCF 10A | NM | Basal B | Olomoucine II | CDK1 | CDK | 26.7 | uM | 11056.147 | 0.0126 | -0.5848 | 2.7832 | |
| MCF 10A | NM | Basal B | Olomoucine II | CDK1 | CDK | 133 | uM | 11056.147 | 0.0127 | -0.5833 | 2.7832 | |
| MCF 10F | NM | - | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 12254.147 | 1.1251 | 1.1716 | 1.4316 | |
| MCF 10F | NM | - | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 12254.147 | 1.0989 | 1.1361 | 1.4316 | |
| MCF 10F | NM | - | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 12254.147 | 1.0588 | 1.0815 | 1.4316 | |
| MCF 10F | NM | - | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 12254.147 | 1.1065 | 1.1466 | 1.4316 | |
| MCF 10F | NM | - | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12254.147 | 1.0534 | 1.0740 | 1.4316 | |
| MCF 10F | NM | - | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12254.147 | 1.0176 | 1.0246 | 1.4316 | |
| MCF 10F | NM | - | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12254.147 | 0.9157 | 0.8807 | 1.4316 | |
| MCF 10F | NM | - | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12254.147 | 0.0774 | -0.6652 | 1.4316 |