Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 12178.147 | 1.0827 | 1.2938 | 0.5795 | |
| BT-474 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12178.147 | 1.1031 | 1.3691 | 0.5795 | |
| BT-474 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12178.147 | 0.9803 | 0.9325 | 0.5795 | |
| BT-474 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12178.147 | 0.9076 | 0.6919 | 0.5795 | |
| BT-474 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12178.147 | 0.7432 | 0.1983 | 0.5795 | |
| BT-474 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 12178.147 | 0.7459 | 0.2058 | 0.5795 | |
| BT-474 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 12291.147 | 1.0338 | 1.1143 | 0.5980 | |
| BT-474 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 12291.147 | 1.1163 | 1.4039 | 0.5980 | |
| BT-474 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 12291.147 | 1.0282 | 1.0954 | 0.5980 | |
| BT-474 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 12291.147 | 0.9390 | 0.8003 | 0.5980 | |
| BT-474 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12291.147 | 0.9332 | 0.7816 | 0.5980 | |
| BT-474 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12291.147 | 1.0197 | 1.0663 | 0.5980 | |
| BT-474 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12291.147 | 0.8407 | 0.4964 | 0.5980 | |
| BT-474 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12291.147 | 0.6702 | 0.0242 | 0.5980 | |
| BT-474 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 12291.147 | 0.6469 | -0.0345 | 0.5980 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 10696.147 | 0.9682 | 0.8687 | 0.4763 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 10696.147 | 0.9210 | 0.6827 | 0.4763 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 10696.147 | 0.9360 | 0.7408 | 0.4763 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 10696.147 | 0.9432 | 0.7690 | 0.4763 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 10696.147 | 0.9512 | 0.8006 | 0.4763 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 10696.147 | 0.9404 | 0.7581 | 0.4763 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 10696.147 | 0.8883 | 0.5598 | 0.4763 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 10696.147 | 0.4898 | -0.5531 | 0.4763 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 10696.147 | 0.7463 | 0.0819 | 0.4763 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 11855.147 | 0.9632 | 0.8730 | 0.5719 |