Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 11855.147 | 0.8833 | 0.6099 | 0.5719 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 11855.147 | 1.0003 | 1.0011 | 0.5719 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 11855.147 | 0.9545 | 0.8436 | 0.5719 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 11855.147 | 0.9664 | 0.8840 | 0.5719 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 11855.147 | 1.0053 | 1.0185 | 0.5719 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 11855.147 | 0.8830 | 0.6088 | 0.5719 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 11855.147 | 0.4379 | -0.5280 | 0.5719 | |
| BT-483 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 11855.147 | 0.6173 | -0.1397 | 0.5719 | |
| BT-549 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 12305.147 | 1.0391 | 1.0268 | 2.8865 | |
| BT-549 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 12305.147 | 1.0354 | 1.0243 | 2.8865 | |
| BT-549 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 12305.147 | 1.0852 | 1.0574 | 2.8865 | |
| BT-549 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 12305.147 | 1.0343 | 1.0235 | 2.8865 | |
| BT-549 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12305.147 | 0.9947 | 0.9963 | 2.8865 | |
| BT-549 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12305.147 | 0.7583 | 0.8172 | 2.8865 | |
| BT-549 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12305.147 | 0.2689 | 0.2689 | 2.8865 | |
| BT-549 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12305.147 | 0.0922 | -0.1244 | 2.8865 | |
| BT-549 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 133 | uM | 12305.147 | 0.0864 | -0.1436 | 2.8865 | |
| CAMA-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 10755.147 | 0.9977 | 0.9924 | 0.6156 | |
| CAMA-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 10755.147 | 0.9248 | 0.7613 | 0.6156 | |
| CAMA-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 10755.147 | 0.9693 | 0.9011 | 0.6156 | |
| CAMA-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 10755.147 | 0.9759 | 0.9222 | 0.6156 | |
| CAMA-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 10755.147 | 0.9958 | 0.9862 | 0.6156 | |
| CAMA-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 10755.147 | 0.9689 | 0.8998 | 0.6156 | |
| CAMA-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 10755.147 | 0.9012 | 0.6889 | 0.6156 | |
| CAMA-1 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 10755.147 | 0.4575 | -0.4385 | 0.6156 |