Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 10381.066 | 0.9577 | 0.9412 | 1.4484 | |
| SUM1315MO2 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 10381.066 | 0.8843 | 0.8372 | 1.4484 | |
| SUM1315MO2 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 10381.066 | 0.7565 | 0.6496 | 1.4484 | |
| SUM1315MO2 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 10381.066 | 0.1841 | -0.3782 | 1.4484 | |
| SUM149PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7530.066 | 0.9743 | 0.9737 | 1.9710 | |
| SUM149PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7530.066 | 1.0056 | 1.0057 | 1.9710 | |
| SUM149PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7530.066 | 0.9846 | 0.9843 | 1.9710 | |
| SUM149PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7530.066 | 1.0222 | 1.0224 | 1.9710 | |
| SUM149PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7530.066 | 1.0555 | 1.0556 | 1.9710 | |
| SUM149PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7530.066 | 0.9571 | 0.9560 | 1.9710 | |
| SUM149PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7530.066 | 0.9524 | 0.9511 | 1.9710 | |
| SUM149PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7530.066 | 0.8626 | 0.8555 | 1.9710 | |
| SUM149PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7530.066 | 0.1563 | -0.2200 | 1.9710 | |
| SUM159PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7531.066 | 0.9762 | 0.9855 | 3.3129 | |
| SUM159PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7531.066 | 1.0217 | 1.0130 | 3.3129 | |
| SUM159PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7531.066 | 0.9729 | 0.9835 | 3.3129 | |
| SUM159PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7531.066 | 1.0180 | 1.0108 | 3.3129 | |
| SUM159PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7531.066 | 1.0425 | 1.0253 | 3.3129 | |
| SUM159PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7531.066 | 1.0669 | 1.0395 | 3.3129 | |
| SUM159PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7531.066 | 1.0591 | 1.0350 | 3.3129 | |
| SUM159PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7531.066 | 0.8620 | 0.9123 | 3.3129 | |
| SUM159PT | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7531.066 | 0.3301 | 0.4313 | 3.3129 | |
| SUM185PE | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7532.066 | 0.9395 | 0.8661 | 0.9011 | |
| SUM185PE | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7532.066 | 1.0230 | 1.0512 | 0.9011 | |
| SUM185PE | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7532.066 | 0.9642 | 0.9207 | 0.9011 |