Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 2.67 | uM | 10939.147 | 0.2510 | -0.1048 | 1.7195 | |
| T47D | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 13.3 | uM | 10939.147 | 0.0179 | -0.8074 | 1.7195 | |
| T47D | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 66.7 | uM | 10939.147 | 0.0117 | -0.8498 | 1.7195 | |
| T47DKBLUC | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 12608.147 | 0.9378 | 0.9036 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 12608.147 | 0.9475 | 0.9188 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 12608.147 | 0.9828 | 0.9735 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 12608.147 | 0.9352 | 0.8997 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 0.107 | uM | 12608.147 | 0.9483 | 0.9200 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 0.533 | uM | 12608.147 | 0.8337 | 0.7391 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 2.67 | uM | 12608.147 | 0.4921 | 0.1597 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 13.3 | uM | 12608.147 | 0.0189 | -0.9054 | 1.3009 | |
| T47DKBLUC | Unknown | Unknown | Oxamflatin | HDAC | HDAC | 66.7 | uM | 12608.147 | 0.0212 | -0.8964 | 1.3009 | |
| UACC-812 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 10754.147 | 1.0313 | 1.0488 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 10754.147 | 1.0081 | 1.0126 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 10754.147 | 1.1020 | 1.1577 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 10754.147 | 1.0586 | 1.0910 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.107 | uM | 10754.147 | 0.9088 | 0.8559 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.533 | uM | 10754.147 | 0.7719 | 0.6335 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 2.67 | uM | 10754.147 | 0.5473 | 0.2486 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 13.3 | uM | 10754.147 | 0.2959 | -0.2279 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 66.7 | uM | 10754.147 | 0.0013 | -0.9886 | 1.2793 | |
| UACC-812 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 11938.147 | 0.8676 | 0.6213 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 11938.147 | 0.8804 | 0.6567 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 11938.147 | 0.9348 | 0.8103 | 0.6765 | |
| UACC-812 | HER2amp | Luminal | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 11938.147 | 0.9408 | 0.8275 | 0.6765 |