Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 11057.147 | 0.8979 | 0.9466 | 3.9818 | |
| SUM159PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 11057.147 | 1.0011 | 1.0006 | 3.9818 | |
| SUM159PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 11057.147 | 0.9633 | 0.9813 | 3.9818 | |
| SUM159PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.213 | uM | 11057.147 | 0.9162 | 0.9565 | 3.9818 | |
| SUM159PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 1.07 | uM | 11057.147 | 0.9250 | 0.9612 | 3.9818 | |
| SUM159PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 5.33 | uM | 11057.147 | 0.4728 | 0.6570 | 3.9818 | |
| SUM159PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 26.7 | uM | 11057.147 | 0.0890 | 0.0892 | 3.9818 | |
| SUM159PT | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 133 | uM | 11057.147 | 0.0778 | 0.0532 | 3.9818 | |
| SUM185PE | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 12269.147 | 1.0163 | 1.0384 | 0.8519 | |
| SUM185PE | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 12269.147 | 1.0113 | 1.0265 | 0.8519 | |
| SUM185PE | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 12269.147 | 1.0839 | 1.1984 | 0.8519 | |
| SUM185PE | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 12269.147 | 0.9679 | 0.9249 | 0.8519 | |
| SUM185PE | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12269.147 | 0.4417 | -0.2335 | 0.8519 | |
| SUM185PE | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12269.147 | 0.9551 | 0.8950 | 0.8519 | |
| SUM185PE | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12269.147 | 0.8715 | 0.7018 | 0.8519 | |
| SUM185PE | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12269.147 | 0.2563 | -0.5955 | 0.8519 | |
| SUM185PE | TNBC | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 12269.147 | 0.3006 | -0.5122 | 0.8519 | |
| SUM225CWN | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 12098.147 | 0.9712 | 0.9516 | 1.1904 | |
| SUM225CWN | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 12098.147 | 1.0838 | 1.1398 | 1.1904 | |
| SUM225CWN | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 12098.147 | 0.9800 | 0.9664 | 1.1904 | |
| SUM225CWN | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 12098.147 | 0.9513 | 0.9179 | 1.1904 | |
| SUM225CWN | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12098.147 | 0.8531 | 0.7500 | 1.1904 | |
| SUM225CWN | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12098.147 | 1.1165 | 1.1941 | 1.1904 | |
| SUM225CWN | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12098.147 | 0.7011 | 0.4842 | 1.1904 | |
| SUM225CWN | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12098.147 | 0.3427 | -0.1866 | 1.1904 |