Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10873.152 | 1.0541 | 1.0931 | 1.1577 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10873.152 | 0.9894 | 0.9817 | 1.1577 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10873.152 | 1.0325 | 1.0561 | 1.1577 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10873.152 | 0.8534 | 0.7441 | 1.1577 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10873.152 | 0.8777 | 0.7869 | 1.1577 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10873.152 | 0.4236 | -0.0476 | 1.1577 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10873.152 | 0.0100 | -0.9625 | 1.1577 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 167 | uM | 10873.152 | 0.0117 | -0.9571 | 1.1577 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12400.152 | 1.0078 | 1.0137 | 1.1392 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12400.152 | 0.9337 | 0.8832 | 1.1392 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12400.152 | 0.9529 | 0.9171 | 1.1392 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12400.152 | 0.9447 | 0.9026 | 1.1392 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12400.152 | 1.0013 | 1.0022 | 1.1392 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12400.152 | 0.9292 | 0.8751 | 1.1392 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12400.152 | 0.3999 | -0.1054 | 1.1392 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12400.152 | 0.0226 | -0.9283 | 1.1392 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 167 | uM | 12400.152 | 0.0199 | -0.9357 | 1.1392 | |
| Hs 578T | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10694.152 | 1.0096 | 1.0079 | 2.4238 | |
| Hs 578T | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10694.152 | 0.9557 | 0.9630 | 2.4238 | |
| Hs 578T | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10694.152 | 0.9825 | 0.9855 | 2.4238 | |
| Hs 578T | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10694.152 | 1.0117 | 1.0096 | 2.4238 | |
| Hs 578T | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10694.152 | 0.9535 | 0.9611 | 2.4238 | |
| Hs 578T | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10694.152 | 0.7818 | 0.8069 | 2.4238 | |
| Hs 578T | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10694.152 | 0.0070 | -0.7413 | 2.4238 | |
| Hs 578T | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10694.152 | 0.0064 | -0.7515 | 2.4238 |