Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12220.159 | 0.9572 | 0.8253 | 0.4788 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12220.159 | 1.0171 | 1.0719 | 0.4788 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12220.159 | 0.9702 | 0.8776 | 0.4788 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12220.159 | 0.7099 | -0.0223 | 0.4788 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12220.159 | 0.1217 | -0.9754 | 0.4788 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12220.159 | 0.0091 | -0.9999 | 0.4788 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12220.159 | 0.0134 | -0.9998 | 0.4788 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 167 | uM | 12220.159 | 0.0194 | -0.9995 | 0.4788 | |
| SK-BR-3 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 11851.159 | 0.9630 | 0.9410 | 1.2582 | |
| SK-BR-3 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 11851.159 | 0.9551 | 0.9283 | 1.2582 | |
| SK-BR-3 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 11851.159 | 1.0022 | 1.0035 | 1.2582 | |
| SK-BR-3 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 11851.159 | 1.0330 | 1.0523 | 1.2582 | |
| SK-BR-3 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 11851.159 | 0.9249 | 0.8796 | 1.2582 | |
| SK-BR-3 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 11851.159 | 0.7235 | 0.5463 | 1.2582 | |
| SK-BR-3 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 11851.159 | 0.0517 | -0.8100 | 1.2582 | |
| SK-BR-3 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 11851.159 | 0.0086 | -0.9542 | 1.2582 | |
| SK-BR-3 | HER2amp | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 11851.159 | 0.0101 | -0.9481 | 1.2582 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10875.152 | 0.9510 | 0.8697 | 0.7465 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10875.152 | 0.9537 | 0.8769 | 0.7465 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10875.152 | 0.9818 | 0.9514 | 0.7465 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10875.152 | 1.0248 | 1.0666 | 0.7465 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10875.152 | 0.9040 | 0.7472 | 0.7465 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10875.152 | 0.7299 | 0.3117 | 0.7465 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10875.152 | 0.1490 | -0.8439 | 0.7465 | |
| SUM1315MO2 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10875.152 | 0.0098 | -0.9959 | 0.7465 |