Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10937.152 | 1.0479 | 1.0776 | 1.2272 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10937.152 | 0.9456 | 0.9109 | 1.2272 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10937.152 | 0.8402 | 0.7355 | 1.2272 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10937.152 | 0.0797 | -0.7453 | 1.2272 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10937.152 | 0.0085 | -0.9589 | 1.2272 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 167 | uM | 10937.152 | 0.0049 | -0.9740 | 1.2272 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10578.14 | 1.0128 | 1.0153 | 1.6718 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10578.14 | 0.9373 | 0.9241 | 1.6718 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10578.14 | 0.9672 | 0.9606 | 1.6718 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10578.14 | 0.9169 | 0.8988 | 1.6718 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10578.14 | 0.9667 | 0.9598 | 1.6718 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10578.14 | 0.8196 | 0.7756 | 1.6718 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10578.14 | 0.1274 | -0.4169 | 1.6718 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10578.14 | 0.0124 | -0.8553 | 1.6718 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 167 | uM | 10578.14 | 0.0003 | -0.9845 | 1.6718 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 11850.159 | 0.9477 | 0.9451 | 1.9270 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 11850.159 | 0.9426 | 0.9396 | 1.9270 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 11850.159 | 0.9628 | 0.9611 | 1.9270 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 11850.159 | 0.9978 | 0.9977 | 1.9270 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.267 | uM | 11850.159 | 0.9010 | 0.8946 | 1.9270 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 1.33 | uM | 11850.159 | 0.8044 | 0.7864 | 1.9270 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 6.67 | uM | 11850.159 | 0.1390 | -0.2817 | 1.9270 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 33.3 | uM | 11850.159 | 0.0122 | -0.7965 | 1.9270 | |
| HCC38 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 167 | uM | 11850.159 | 0.0069 | -0.8493 | 1.9270 | |
| HCC70 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10873.152 | 0.9539 | 0.9200 | 1.1577 |