Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12414.152 | 0.9544 | 0.9193 | 1.1325 | |
| MDA-MB-453 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12414.152 | 1.0112 | 1.0198 | 1.1325 | |
| MDA-MB-453 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12414.152 | 0.9985 | 0.9973 | 1.1325 | |
| MDA-MB-453 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12414.152 | 0.3547 | -0.1992 | 1.1325 | |
| MDA-MB-453 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12414.152 | 0.0149 | -0.9511 | 1.1325 | |
| MDA-MB-453 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 12414.152 | 0.0159 | -0.9484 | 1.1325 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10644.14 | 1.0300 | 1.1424 | 0.4302 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10644.14 | 0.9779 | 0.8988 | 0.4302 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10644.14 | 1.0453 | 1.2169 | 0.4302 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10644.14 | 0.9696 | 0.8617 | 0.4302 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10644.14 | 1.0950 | 1.4697 | 0.4302 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10644.14 | 0.3423 | -0.8346 | 0.4302 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10644.14 | 0.0053 | -1.0000 | 0.4302 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10644.14 | 0.0104 | -1.0000 | 0.4302 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 167 | uM | 10644.14 | 0.0143 | -0.9999 | 0.4302 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10874.152 | 0.9722 | 0.9282 | 0.7706 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10874.152 | 1.0056 | 1.0146 | 0.7706 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10874.152 | 1.0331 | 1.0863 | 0.7706 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10874.152 | 1.1150 | 1.3035 | 0.7706 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10874.152 | 0.9628 | 0.9040 | 0.7706 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10874.152 | 0.4348 | -0.3213 | 0.7706 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10874.152 | 0.0089 | -0.9957 | 0.7706 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10874.152 | 0.0123 | -0.9934 | 0.7706 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 167 | uM | 10874.152 | 0.0109 | -0.9943 | 0.7706 | |
| MX1 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12220.159 | 0.9673 | 0.8657 | 0.4788 |