Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10996.152 | 0.8221 | 0.4686 | 0.6343 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10996.152 | 0.0073 | -0.9991 | 0.6343 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10996.152 | 0.0125 | -0.9980 | 0.6343 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 10996.152 | 0.0082 | -0.9990 | 0.6343 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12192.159 | 0.8885 | 0.7319 | 0.8215 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12192.159 | 0.9584 | 0.8991 | 0.8215 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12192.159 | 0.9344 | 0.8415 | 0.8215 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12192.159 | 1.0086 | 1.0210 | 0.8215 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12192.159 | 0.7884 | 0.4974 | 0.8215 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12192.159 | 0.7078 | 0.3132 | 0.8215 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12192.159 | 0.0110 | -0.9917 | 0.8215 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12192.159 | 0.0104 | -0.9923 | 0.8215 | |
| HCC2185 | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 12192.159 | 0.0093 | -0.9933 | 0.8215 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10577.14 | 1.0387 | 1.0797 | 0.9722 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10577.14 | 0.9958 | 0.9914 | 0.9722 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10577.14 | 0.9842 | 0.9674 | 0.9722 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10577.14 | 0.9957 | 0.9912 | 0.9722 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10577.14 | 1.0389 | 1.0801 | 0.9722 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10577.14 | 0.9459 | 0.8887 | 0.9722 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10577.14 | 0.1659 | -0.6848 | 0.9722 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10577.14 | 0.0105 | -0.9817 | 0.9722 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 167 | uM | 10577.14 | 0.0106 | -0.9813 | 0.9722 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10937.152 | 1.0289 | 1.0470 | 1.2272 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10937.152 | 1.1128 | 1.1820 | 1.2272 | |
| HCC3153 | TNBC | Basal A | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10937.152 | 0.9904 | 0.9843 | 1.2272 |