Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 6.67 | uM | 11937.159 | 0.0272 | -0.6055 | 2.2200 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 33.3 | uM | 11937.159 | 0.0077 | -0.7767 | 2.2200 | |
| SUM149PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 167 | uM | 11937.159 | 0.0058 | -0.8038 | 2.2200 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10520.14 | 1.0704 | 1.0371 | 3.7031 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10520.14 | 0.8542 | 0.9167 | 3.7031 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10520.14 | 1.0381 | 1.0203 | 3.7031 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10520.14 | 0.9508 | 0.9729 | 3.7031 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10520.14 | 1.1027 | 1.0535 | 3.7031 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10520.14 | 0.5115 | 0.6688 | 3.7031 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10520.14 | 0.0008 | -0.7051 | 3.7031 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10520.14 | 0.0255 | -0.2578 | 3.7031 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 167 | uM | 10520.14 | 0.0008 | -0.7051 | 3.7031 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 11057.152 | 1.0950 | 1.0476 | 3.8541 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 11057.152 | 0.9607 | 0.9793 | 3.8541 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 11057.152 | 0.9830 | 0.9911 | 3.8541 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 11057.152 | 1.0504 | 1.0257 | 3.8541 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.267 | uM | 11057.152 | 0.9727 | 0.9857 | 3.8541 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 1.33 | uM | 11057.152 | 0.7816 | 0.8761 | 3.8541 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 6.67 | uM | 11057.152 | 0.0210 | -0.2662 | 3.8541 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 33.3 | uM | 11057.152 | 0.0197 | -0.2778 | 3.8541 | |
| SUM159PT | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 167 | uM | 11057.152 | 0.0004 | -0.7348 | 3.8541 | |
| SUM185PE | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12269.152 | 1.0471 | 1.1076 | 0.8791 | |
| SUM185PE | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12269.152 | 1.0465 | 1.1062 | 0.8791 | |
| SUM185PE | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12269.152 | 1.0554 | 1.1266 | 0.8791 | |
| SUM185PE | TNBC | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12269.152 | 1.0036 | 1.0082 | 0.8791 |