Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | NSC 663284 | CDC25 | CDC | 6.67 | uM | 11056.152 | 0.0547 | -0.2468 | 2.9748 | |
| MCF 10A | NM | Basal B | NSC 663284 | CDC25 | CDC | 33.3 | uM | 11056.152 | 0.0092 | -0.5870 | 2.9748 | |
| MCF 10A | NM | Basal B | NSC 663284 | CDC25 | CDC | 167 | uM | 11056.152 | 0.0086 | -0.5954 | 2.9748 | |
| MCF 10F | NM | - | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12254.152 | 0.9604 | 0.9565 | 1.8382 | |
| MCF 10F | NM | - | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12254.152 | 0.9493 | 0.9442 | 1.8382 | |
| MCF 10F | NM | - | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12254.152 | 0.9553 | 0.9509 | 1.8382 | |
| MCF 10F | NM | - | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12254.152 | 0.9518 | 0.9470 | 1.8382 | |
| MCF 10F | NM | - | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12254.152 | 0.9646 | 0.9612 | 1.8382 | |
| MCF 10F | NM | - | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12254.152 | 0.7950 | 0.7653 | 1.8382 | |
| MCF 10F | NM | - | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12254.152 | 0.2573 | -0.0443 | 1.8382 | |
| MCF 10F | NM | - | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12254.152 | 0.0092 | -0.8440 | 1.8382 | |
| MCF 10F | NM | - | NSC 663284 | CDC25 | CDC | 167 | uM | 12254.152 | 0.0079 | -0.8559 | 1.8382 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10817.152 | 1.0193 | 1.0267 | 1.4414 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10817.152 | 0.9922 | 0.9892 | 1.4414 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10817.152 | 1.0064 | 1.0089 | 1.4414 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10817.152 | 0.9731 | 0.9625 | 1.4414 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10817.152 | 0.9661 | 0.9527 | 1.4414 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10817.152 | 0.8932 | 0.8492 | 1.4414 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10817.152 | 0.0079 | -0.9302 | 1.4414 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10817.152 | 0.0139 | -0.8971 | 1.4414 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 167 | uM | 10817.152 | 0.0098 | -0.9192 | 1.4414 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12365.152 | 1.0606 | 1.0564 | 2.1145 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12365.152 | 0.9549 | 0.9568 | 2.1145 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12365.152 | 1.0465 | 1.0435 | 2.1145 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12365.152 | 1.0116 | 1.0110 | 2.1145 |