Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 167 | uM | 10694.152 | 0.0057 | -0.7631 | 2.4238 | |
| LY2 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10816.152 | 0.8815 | 0.7654 | 1.0111 | |
| LY2 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10816.152 | 1.0167 | 1.0330 | 1.0111 | |
| LY2 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10816.152 | 0.9445 | 0.8901 | 1.0111 | |
| LY2 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10816.152 | 0.8866 | 0.7756 | 1.0111 | |
| LY2 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10816.152 | 0.7955 | 0.5950 | 1.0111 | |
| LY2 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10816.152 | 0.5638 | 0.1348 | 1.0111 | |
| LY2 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10816.152 | 0.0108 | -0.9773 | 1.0111 | |
| LY2 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10816.152 | 0.0141 | -0.9705 | 1.0111 | |
| LY2 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 10816.152 | 0.0125 | -0.9738 | 1.0111 | |
| MB 157 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12580.152 | 0.9578 | 0.9622 | 2.2597 | |
| MB 157 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12580.152 | 0.9974 | 0.9977 | 2.2597 | |
| MB 157 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12580.152 | 0.9931 | 0.9939 | 2.2597 | |
| MB 157 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12580.152 | 1.0146 | 1.0129 | 2.2597 | |
| MB 157 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12580.152 | 0.9795 | 0.9818 | 2.2597 | |
| MB 157 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12580.152 | 0.9061 | 0.9146 | 2.2597 | |
| MB 157 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12580.152 | 0.0058 | -0.7954 | 2.2597 | |
| MB 157 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12580.152 | 0.0102 | -0.7366 | 2.2597 | |
| MB 157 | Unknown | Unknown | NSC 663284 | CDC25 | CDC | 167 | uM | 12580.152 | 0.0086 | -0.7558 | 2.2597 | |
| MCF 10A | NM | Basal B | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 11056.152 | 0.9689 | 0.9789 | 2.9748 | |
| MCF 10A | NM | Basal B | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 11056.152 | 0.9577 | 0.9712 | 2.9748 | |
| MCF 10A | NM | Basal B | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 11056.152 | 0.9825 | 0.9882 | 2.9748 | |
| MCF 10A | NM | Basal B | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 11056.152 | 1.0092 | 1.0062 | 2.9748 | |
| MCF 10A | NM | Basal B | NSC 663284 | CDC25 | CDC | 0.267 | uM | 11056.152 | 0.9545 | 0.9690 | 2.9748 | |
| MCF 10A | NM | Basal B | NSC 663284 | CDC25 | CDC | 1.33 | uM | 11056.152 | 0.7696 | 0.8315 | 2.9748 |