Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12594.147 | 1.0254 | 1.0354 | 1.4279 | |
| MDA-MB-157 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12594.147 | 1.0185 | 1.0258 | 1.4279 | |
| MDA-MB-157 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12594.147 | 0.8245 | 0.7471 | 1.4279 | |
| MDA-MB-157 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12594.147 | 0.1169 | -0.5551 | 1.4279 | |
| MDA-MB-157 | TNBC | Basal B | Olomoucine II | CDK1 | CDK | 133 | uM | 12594.147 | 0.1203 | -0.5462 | 1.4279 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 10642.147 | 1.0636 | 1.1961 | 0.6592 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 10642.147 | 1.0351 | 1.1076 | 0.6592 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 10642.147 | 1.0251 | 1.0767 | 0.6592 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 10642.147 | 1.0553 | 1.1700 | 0.6592 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 10642.147 | 1.0060 | 1.0182 | 0.6592 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 10642.147 | 0.9969 | 0.9906 | 0.6592 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 10642.147 | 0.8638 | 0.6015 | 0.6592 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 10642.147 | 0.6775 | 0.1081 | 0.6592 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 10642.147 | 0.7153 | 0.2032 | 0.6592 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 10818.147 | 0.9757 | 0.9066 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 10818.147 | 0.9444 | 0.7892 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 10818.147 | 0.9790 | 0.9191 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 10818.147 | 0.9442 | 0.7883 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 10818.147 | 0.9476 | 0.8009 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 10818.147 | 0.9670 | 0.8734 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 10818.147 | 0.8102 | 0.3278 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 10818.147 | 0.6304 | -0.1854 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 10818.147 | 0.6595 | -0.1104 | 0.5138 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 12126.147 | 0.9884 | 0.9677 | 0.7140 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 12126.147 | 0.9343 | 0.8183 | 0.7140 |