Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 12126.147 | 0.9838 | 0.9547 | 0.7140 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 12126.147 | 0.9508 | 0.8637 | 0.7140 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12126.147 | 0.9885 | 0.9679 | 0.7140 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12126.147 | 0.9963 | 0.9896 | 0.7140 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12126.147 | 0.8213 | 0.5179 | 0.7140 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12126.147 | 0.5733 | -0.0825 | 0.7140 | |
| MDA-MB-175-VII | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 12126.147 | 0.3825 | -0.4795 | 0.7140 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 10643.147 | 1.0588 | 1.1884 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 10643.147 | 1.0215 | 1.0681 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 10643.147 | 0.9754 | 0.9230 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 10643.147 | 0.9487 | 0.8408 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 10643.147 | 1.0457 | 1.1457 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 10643.147 | 1.0110 | 1.0348 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 10643.147 | 1.0531 | 1.1698 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 10643.147 | 0.4630 | -0.4055 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 10643.147 | 0.5059 | -0.3165 | 0.6347 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 10999.147 | 0.9562 | 0.9054 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 10999.147 | 0.9646 | 0.9235 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 10999.147 | 1.0034 | 1.0074 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 10999.147 | 1.0744 | 1.1615 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 10999.147 | 0.9808 | 0.9585 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 10999.147 | 1.0143 | 1.0310 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 10999.147 | 0.9127 | 0.8117 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 10999.147 | 0.4252 | -0.2075 | 0.9239 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 10999.147 | 0.3646 | -0.3288 | 0.9239 |