Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 167 | uM | 12305.152 | 0.0007 | -0.8290 | 2.9694 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10473.14 | 0.9812 | 0.9713 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10473.14 | 0.9843 | 0.9760 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10473.14 | 0.9258 | 0.8859 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10473.14 | 0.9633 | 0.9439 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10473.14 | 0.9565 | 0.9334 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10473.14 | 0.8802 | 0.8147 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10473.14 | 0.2135 | -0.3833 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10473.14 | 0.0092 | -0.9438 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 10473.14 | 0.0090 | -0.9447 | 1.3126 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10755.152 | 0.9599 | 0.8652 | 0.5859 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10755.152 | 0.9386 | 0.7951 | 0.5859 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10755.152 | 0.9662 | 0.8861 | 0.5859 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10755.152 | 0.9836 | 0.9442 | 0.5859 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10755.152 | 0.9251 | 0.7512 | 0.5859 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10755.152 | 0.9330 | 0.7767 | 0.5859 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10755.152 | 0.2235 | -0.8449 | 0.5859 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10755.152 | 0.0128 | -0.9988 | 0.5859 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 10755.152 | 0.0130 | -0.9988 | 0.5859 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12070.159 | 0.9995 | 0.9989 | 0.9846 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12070.159 | 1.0306 | 1.0623 | 0.9846 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12070.159 | 0.9596 | 0.9180 | 0.9846 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12070.159 | 1.0497 | 1.1009 | 0.9846 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12070.159 | 0.9183 | 0.8341 | 0.9846 | |
| CAMA-1 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12070.159 | 0.9549 | 0.9084 | 0.9846 |