Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12365.152 | 1.0169 | 1.0159 | 2.1145 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12365.152 | 0.6758 | 0.6617 | 2.1145 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12365.152 | 0.0116 | -0.7571 | 2.1145 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12365.152 | 0.0113 | -0.7603 | 2.1145 | |
| MCF12A | NM | Basal B | NSC 663284 | CDC25 | CDC | 167 | uM | 12365.152 | 0.0094 | -0.7800 | 2.1145 | |
| MCF7 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10997.152 | 0.9787 | 0.9692 | 1.3917 | |
| MCF7 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10997.152 | 0.9863 | 0.9802 | 1.3917 | |
| MCF7 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10997.152 | 0.9560 | 0.9364 | 1.3917 | |
| MCF7 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10997.152 | 0.9514 | 0.9296 | 1.3917 | |
| MCF7 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10997.152 | 0.9660 | 0.9509 | 1.3917 | |
| MCF7 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10997.152 | 0.9187 | 0.8818 | 1.3917 | |
| MCF7 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10997.152 | 0.3735 | -0.0144 | 1.3917 | |
| MCF7 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10997.152 | 0.0159 | -0.8981 | 1.3917 | |
| MCF7 | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 10997.152 | 0.0158 | -0.8983 | 1.3917 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10519.14 | 1.0081 | 1.0157 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10519.14 | 1.0234 | 1.0455 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10519.14 | 0.9685 | 0.9386 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10519.14 | 0.9748 | 0.9510 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10519.14 | 0.9687 | 0.9389 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10519.14 | 0.8856 | 0.7769 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10519.14 | 0.7298 | 0.4717 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10519.14 | 0.0080 | -0.9818 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 10519.14 | 0.0062 | -0.9858 | 1.0269 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 10998.152 | 0.9516 | 0.8868 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 10998.152 | 0.9810 | 0.9555 | 0.8517 |