Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 10998.152 | 0.9542 | 0.8928 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 10998.152 | 0.9937 | 0.9852 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 10998.152 | 0.9672 | 0.9232 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 10998.152 | 0.9075 | 0.7846 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 10998.152 | 0.7725 | 0.4771 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 10998.152 | 0.0094 | -0.9917 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 10998.152 | 0.0088 | -0.9923 | 0.8517 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12206.159 | 0.9389 | 0.8859 | 1.0742 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12206.159 | 0.9400 | 0.8880 | 1.0742 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12206.159 | 0.9079 | 0.8279 | 1.0742 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12206.159 | 0.9181 | 0.8471 | 1.0742 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12206.159 | 0.9099 | 0.8316 | 1.0742 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12206.159 | 0.9221 | 0.8546 | 1.0742 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12206.159 | 0.6204 | 0.2825 | 1.0742 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12206.159 | 0.0118 | -0.9680 | 1.0742 | |
| MDA-MB-134-VI | HR+ | Luminal | NSC 663284 | CDC25 | CDC | 167 | uM | 12206.159 | 0.0088 | -0.9755 | 1.0742 | |
| MDA-MB-157 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.000427 | uM | 12594.152 | 1.1040 | 1.1571 | 1.3085 | |
| MDA-MB-157 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.00213 | uM | 12594.152 | 1.0414 | 1.0629 | 1.3085 | |
| MDA-MB-157 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0107 | uM | 12594.152 | 1.0920 | 1.1391 | 1.3085 | |
| MDA-MB-157 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.0533 | uM | 12594.152 | 1.0999 | 1.1510 | 1.3085 | |
| MDA-MB-157 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 0.267 | uM | 12594.152 | 1.1767 | 1.2648 | 1.3085 | |
| MDA-MB-157 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 1.33 | uM | 12594.152 | 0.7362 | 0.5826 | 1.3085 | |
| MDA-MB-157 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 6.67 | uM | 12594.152 | 0.0023 | -0.9811 | 1.3085 | |
| MDA-MB-157 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 33.3 | uM | 12594.152 | 0.0049 | -0.9655 | 1.3085 | |
| MDA-MB-157 | TNBC | Basal B | NSC 663284 | CDC25 | CDC | 167 | uM | 12594.152 | 0.0080 | -0.9499 | 1.3085 |