Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 12379.147 | 1.0917 | 1.6327 | 0.3192 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 12379.147 | 1.1482 | 2.0834 | 0.3192 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 12379.147 | 1.1167 | 1.8261 | 0.3192 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 12379.147 | 0.8227 | 0.0852 | 0.3192 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12379.147 | 1.1406 | 2.0201 | 0.3192 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12379.147 | 1.0990 | 1.6882 | 0.3192 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12379.147 | 0.9768 | 0.8581 | 0.3192 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12379.147 | 0.3045 | -0.9518 | 0.3192 | |
| MDA-MB-361 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 12379.147 | 0.2176 | -0.9832 | 0.3192 | |
| MDA-MB-415 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 10938.147 | 1.0114 | 1.0253 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 10938.147 | 0.9027 | 0.7860 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 10938.147 | 1.0048 | 1.0107 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 10938.147 | 0.9940 | 0.9867 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 10938.147 | 0.9271 | 0.8395 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 10938.147 | 0.9078 | 0.7973 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 10938.147 | 0.7827 | 0.5256 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 10938.147 | 0.4630 | -0.1459 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 10938.147 | 0.6260 | 0.1918 | 0.9050 | |
| MDA-MB-415 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 12333.147 | 1.0038 | 1.0110 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 12333.147 | 1.0235 | 1.0693 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 12333.147 | 0.9981 | 0.9944 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 12333.147 | 0.9073 | 0.7343 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12333.147 | 0.9095 | 0.7404 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12333.147 | 1.0181 | 1.0533 | 0.6826 | |
| MDA-MB-415 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12333.147 | 0.4875 | -0.3019 | 0.6826 |