Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 10872.147 | 0.9695 | 0.9623 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 10872.147 | 1.0021 | 1.0025 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 0.213 | uM | 10872.147 | 0.9107 | 0.8882 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 1.07 | uM | 10872.147 | 0.8917 | 0.8639 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 5.33 | uM | 10872.147 | 0.6311 | 0.5068 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 26.7 | uM | 10872.147 | 0.2774 | -0.0912 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 133 | uM | 10872.147 | 0.2408 | -0.1670 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 12523.147 | 0.9691 | 0.9329 | 0.9214 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 12523.147 | 1.0096 | 1.0207 | 0.9214 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 12523.147 | 1.0110 | 1.0239 | 0.9214 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 12523.147 | 1.1085 | 1.2365 | 0.9214 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12523.147 | 1.0071 | 1.0155 | 0.9214 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12523.147 | 1.0094 | 1.0204 | 0.9214 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12523.147 | 0.7945 | 0.5581 | 0.9214 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12523.147 | 0.5384 | 0.0214 | 0.9214 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 133 | uM | 12523.147 | 0.5292 | 0.0025 | 0.9214 | |
| HCC1806 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 12239.147 | 1.0155 | 1.0154 | 2.0027 | |
| HCC1806 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 12239.147 | 0.9966 | 0.9966 | 2.0027 | |
| HCC1806 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 12239.147 | 0.9755 | 0.9754 | 2.0027 | |
| HCC1806 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 12239.147 | 1.0473 | 1.0467 | 2.0027 | |
| HCC1806 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12239.147 | 0.9814 | 0.9814 | 2.0027 | |
| HCC1806 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12239.147 | 0.9310 | 0.9298 | 2.0027 | |
| HCC1806 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12239.147 | 0.8201 | 0.8114 | 2.0027 | |
| HCC1806 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12239.147 | 0.0681 | -0.4772 | 2.0027 | |
| HCC1806 | TNBC | Basal A | Olomoucine II | CDK1 | CDK | 133 | uM | 12239.147 | 0.0367 | -0.6158 | 2.0027 |