Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 12001.147 | 0.8717 | 0.5902 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 12001.147 | 0.9621 | 0.8751 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 12001.147 | 0.8056 | 0.3940 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 12001.147 | 0.4809 | -0.4109 | 0.5989 | |
| HCC1419 | HER2amp | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 12001.147 | 0.3179 | -0.7048 | 0.5989 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 10693.147 | 1.0163 | 1.0368 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 10693.147 | 0.9853 | 0.9668 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 10693.147 | 1.0138 | 1.0311 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 10693.147 | 1.0003 | 1.0006 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 10693.147 | 0.9439 | 0.8742 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 10693.147 | 0.8741 | 0.7188 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 10693.147 | 0.7779 | 0.5072 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 10693.147 | 0.4668 | -0.1520 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 10693.147 | 0.3829 | -0.3216 | 0.8879 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 11936.147 | 0.9588 | 0.9105 | 0.9187 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 11936.147 | 0.8761 | 0.7319 | 0.9187 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.00853 | uM | 11936.147 | 0.9895 | 0.9771 | 0.9187 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.0427 | uM | 11936.147 | 0.9570 | 0.9066 | 0.9187 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 0.213 | uM | 11936.147 | 0.9398 | 0.8693 | 0.9187 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 1.07 | uM | 11936.147 | 0.9520 | 0.8958 | 0.9187 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 5.33 | uM | 11936.147 | 0.7740 | 0.5134 | 0.9187 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 26.7 | uM | 11936.147 | 0.3669 | -0.3284 | 0.9187 | |
| HCC1428 | HR+ | Luminal | Olomoucine II | CDK1 | CDK | 133 | uM | 11936.147 | 0.2305 | -0.5951 | 0.9187 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 0.000341 | uM | 10872.147 | 0.9464 | 0.9333 | 1.6255 | |
| HCC1569 | HER2amp | Basal A | Olomoucine II | CDK1 | CDK | 0.00171 | uM | 10872.147 | 0.9363 | 0.9206 | 1.6255 |