Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7543.066 | 0.8657 | 0.8162 | 1.4960 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7543.066 | 0.8657 | 0.8162 | 1.4960 | |
| T47D | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7543.066 | 0.3254 | -0.0557 | 1.4960 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7544.066 | 0.9553 | 0.9178 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7544.066 | 0.9639 | 0.9336 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7544.066 | 0.9828 | 0.9684 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7544.066 | 0.9474 | 0.9033 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7544.066 | 1.0223 | 1.0408 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7544.066 | 0.9465 | 0.9016 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7544.066 | 0.9540 | 0.9154 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7544.066 | 0.9727 | 0.9498 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7544.066 | 0.6625 | 0.3707 | 1.0898 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7545.066 | 0.9146 | 0.8626 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7545.066 | 0.9269 | 0.8825 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7545.066 | 0.9011 | 0.8407 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7545.066 | 0.9901 | 0.9842 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7545.066 | 0.9671 | 0.9475 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7545.066 | 0.9878 | 0.9806 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7545.066 | 0.9433 | 0.9090 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7545.066 | 0.8619 | 0.7765 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7545.066 | 0.4111 | -0.0153 | 1.2546 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7546.066 | 0.9460 | 0.8770 | 0.8758 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7546.066 | 1.0070 | 1.0161 | 0.8758 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7546.066 | 1.0339 | 1.0775 | 0.8758 | |
| T47DKBLUC | Unknown | Unknown | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7546.066 | 0.9967 | 0.9924 | 0.8758 |