Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-231	TNBC	Basal B	Nutlin 3a	MDM2	MDM2	66.7	uM	7504.066	0.6950	0.6427	1.8487
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.000171	uM	7506.066	0.9650	0.9388	1.1486
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.000853	uM	7506.066	0.9936	0.9889	1.1486
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.00427	uM	7506.066	0.9165	0.8538	1.1486
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.0213	uM	7506.066	0.9396	0.8944	1.1486
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.107	uM	7506.066	0.9757	0.9575	1.1486
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.533	uM	7506.066	0.9741	0.9549	1.1486
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	2.67	uM	7506.066	0.9254	0.8694	1.1486
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	13.3	uM	7506.066	0.9840	0.9720	1.1486
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	66.7	uM	7506.066	0.5017	0.0971	1.1486
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.000171	uM	7507.066	0.9473	0.8848	0.9124
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.000853	uM	7507.066	0.9519	0.8947	0.9124
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.00427	uM	7507.066	0.9428	0.8750	0.9124
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.0213	uM	7507.066	0.9378	0.8642	0.9124
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.107	uM	7507.066	0.9328	0.8533	0.9124
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.533	uM	7507.066	0.9485	0.8874	0.9124
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	2.67	uM	7507.066	0.9147	0.8138	0.9124
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	13.3	uM	7507.066	0.9602	0.9128	0.9124
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	66.7	uM	7507.066	0.7503	0.4598	0.9124
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.000171	uM	7508.066	1.0024	1.0054	0.8980
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.000853	uM	7508.066	0.9518	0.8929	0.8980
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.00427	uM	7508.066	0.9577	0.9061	0.8980
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.0213	uM	7508.066	0.8945	0.7665	0.8980
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.107	uM	7508.066	0.9645	0.9211	0.8980
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.533	uM	7508.066	0.9020	0.7830	0.8980

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)