Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7469.066 | 0.9584 | 0.9580 | 2.0057 | |
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7469.066 | 0.9806 | 0.9805 | 2.0057 | |
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7469.066 | 0.9757 | 0.9756 | 2.0057 | |
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7469.066 | 1.0136 | 1.0135 | 2.0057 | |
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7469.066 | 0.9785 | 0.9784 | 2.0057 | |
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7469.066 | 1.0619 | 1.0608 | 2.0057 | |
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7469.066 | 0.9219 | 0.9205 | 2.0057 | |
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7469.066 | 0.2906 | 0.0801 | 2.0057 | |
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 10418.066 | 0.9654 | 0.9399 | 1.1532 | |
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 10418.066 | 0.9937 | 0.9890 | 1.1532 | |
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 10418.066 | 0.9392 | 0.8941 | 1.1532 | |
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 10418.066 | 1.0394 | 1.0682 | 1.1532 | |
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 10418.066 | 0.9962 | 0.9935 | 1.1532 | |
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 10418.066 | 0.9082 | 0.8398 | 1.1532 | |
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 10418.066 | 0.9319 | 0.8813 | 1.1532 | |
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 10418.066 | 0.8260 | 0.6944 | 1.1532 | |
| HCC38 | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 10418.066 | 0.4087 | -0.0794 | 1.1532 | |
| HCC70 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7470.066 | 0.9563 | 0.9186 | 1.0766 | |
| HCC70 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7470.066 | 0.9491 | 0.9052 | 1.0766 | |
| HCC70 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7470.066 | 0.9451 | 0.8978 | 1.0766 | |
| HCC70 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7470.066 | 1.0210 | 1.0390 | 1.0766 | |
| HCC70 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7470.066 | 0.9989 | 0.9979 | 1.0766 | |
| HCC70 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7470.066 | 0.8906 | 0.7960 | 1.0766 | |
| HCC70 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7470.066 | 0.9084 | 0.8293 | 1.0766 | |
| HCC70 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7470.066 | 0.8210 | 0.6652 | 1.0766 |