Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	2.67	uM	7508.066	0.8985	0.7753	0.8980
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	13.3	uM	7508.066	0.9407	0.8683	0.8980
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	66.7	uM	7508.066	0.9134	0.8080	0.8980
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.000171	uM	10472.066	0.9795	0.9446	0.7390
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.000853	uM	10472.066	0.9458	0.8548	0.7390
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.00427	uM	10472.066	1.0051	1.0137	0.7390
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.0213	uM	10472.066	0.9838	0.9562	0.7390
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.107	uM	10472.066	0.9631	0.9008	0.7390
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	0.533	uM	10472.066	0.9328	0.8203	0.7390
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	2.67	uM	10472.066	0.9510	0.8685	0.7390
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	13.3	uM	10472.066	0.8803	0.6832	0.7390
MDA-MB-361	HER2amp	Luminal	Nutlin 3a	MDM2	MDM2	66.7	uM	10472.066	0.2004	-0.7729	0.7390
MDA-MB-415	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.000171	uM	7510.066	0.8221	0.6160	0.9189
MDA-MB-415	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.000853	uM	7510.066	0.9578	0.9083	0.9189
MDA-MB-415	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.00427	uM	7510.066	0.8777	0.7353	0.9189
MDA-MB-415	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.0213	uM	7510.066	0.8803	0.7409	0.9189
MDA-MB-415	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.107	uM	7510.066	0.8906	0.7631	0.9189
MDA-MB-415	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.533	uM	7510.066	0.9301	0.8483	0.9189
MDA-MB-415	HR+	Luminal	Nutlin 3a	MDM2	MDM2	2.67	uM	7510.066	0.8383	0.6506	0.9189
MDA-MB-415	HR+	Luminal	Nutlin 3a	MDM2	MDM2	13.3	uM	7510.066	0.8469	0.6691	0.9189
MDA-MB-415	HR+	Luminal	Nutlin 3a	MDM2	MDM2	66.7	uM	7510.066	0.6980	0.3525	0.9189
MDA-MB-415	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.000171	uM	7511.066	0.9726	0.9530	1.1691
MDA-MB-415	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.000853	uM	7511.066	1.0013	1.0021	1.1691
MDA-MB-415	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.00427	uM	7511.066	0.9901	0.9830	1.1691
MDA-MB-415	HR+	Luminal	Nutlin 3a	MDM2	MDM2	0.0213	uM	7511.066	1.0545	1.0928	1.1691

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)