Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-468 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7909.075 | 1.0229 | 1.0298 | 1.5307 | |
| MDA-MB-468 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.04 | uM | 7909.075 | 0.7956 | 0.7225 | 1.5307 | |
| MDA-MB-468 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7909.075 | 0.9083 | 0.8783 | 1.5307 | |
| MDA-MB-468 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7909.075 | 0.4495 | 0.1862 | 1.5307 | |
| MDA-MB-468 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7909.075 | 0.0618 | -0.6756 | 1.5307 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9759.011 | 1.0176 | 1.0288 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9759.011 | 1.0144 | 1.0236 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9759.011 | 1.0147 | 1.0242 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9759.011 | 0.9406 | 0.9017 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9759.011 | 0.8442 | 0.7398 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9759.011 | 0.4961 | 0.1233 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9759.011 | 0.1776 | -0.5175 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9759.011 | 0.0577 | -0.8088 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9759.011 | 0.0262 | -0.9000 | 1.2153 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9760.011 | 1.1553 | 1.3233 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9760.011 | 1.1172 | 1.2439 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9760.011 | 1.1565 | 1.3258 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9760.011 | 0.9218 | 0.8379 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9760.011 | 0.9176 | 0.8292 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9760.011 | 0.6989 | 0.3788 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9760.011 | 0.2009 | -0.6221 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9760.011 | 0.0437 | -0.9225 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9760.011 | 0.0110 | -0.9814 | 0.9634 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 10127.12 | 0.9782 | 0.9152 | 0.5076 | |
| SK-BR-3 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 10127.12 | 1.1250 | 1.5225 | 0.5076 |