Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7470.066 | 0.2518 | -0.4446 | 1.0766 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7471.066 | 0.9500 | 0.9557 | 2.2865 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7471.066 | 1.0018 | 1.0016 | 2.2865 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7471.066 | 0.9644 | 0.9685 | 2.2865 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7471.066 | 1.0320 | 1.0277 | 2.2865 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7471.066 | 1.0384 | 1.0332 | 2.2865 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7471.066 | 0.9285 | 0.9362 | 2.2865 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7471.066 | 0.8806 | 0.8919 | 2.2865 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7471.066 | 0.7950 | 0.8091 | 2.2865 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7471.066 | 0.3911 | 0.3265 | 2.2865 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7472.066 | 0.9789 | 0.9769 | 1.8363 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7472.066 | 1.1338 | 1.1415 | 1.8363 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7472.066 | 0.9937 | 0.9931 | 1.8363 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7472.066 | 1.0552 | 1.0594 | 1.8363 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7472.066 | 1.2498 | 1.2582 | 1.8363 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7472.066 | 1.2681 | 1.2762 | 1.8363 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7472.066 | 1.2575 | 1.2658 | 1.8363 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7472.066 | 1.2023 | 1.2110 | 1.8363 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7472.066 | 0.9336 | 0.9265 | 1.8363 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7473.066 | 2.0859 | 1.7317 | 2.3582 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7473.066 | 2.2673 | 1.8300 | 2.3582 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7473.066 | 2.3046 | 1.8496 | 2.3582 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7473.066 | 1.3416 | 1.2655 | 2.3582 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7473.066 | 1.0087 | 1.0073 | 2.3582 | |
| Hs 578T | TNBC | Basal B | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7473.066 | 1.4109 | 1.3143 | 2.3582 |