Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	25.2	uM	9551.011	0.5812	0.6447	2.7742
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	126	uM	9551.011	0.2644	0.2382	2.7742
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	629	uM	9551.011	0.0100	-0.6193	2.7742
MCF 10F	NM	-	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00161	uM	9566.011	1.0048	1.0041	2.3358
MCF 10F	NM	-	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00805	uM	9566.011	0.9978	0.9981	2.3358
MCF 10F	NM	-	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.0403	uM	9566.011	1.0457	1.0387	2.3358
MCF 10F	NM	-	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.201	uM	9566.011	0.9332	0.9417	2.3358
MCF 10F	NM	-	Oxaliplatin	DNA cross-linker	DNA cross-linker	1.01	uM	9566.011	0.6655	0.6800	2.3358
MCF 10F	NM	-	Oxaliplatin	DNA cross-linker	DNA cross-linker	5.03	uM	9566.011	0.5279	0.5214	2.3358
MCF 10F	NM	-	Oxaliplatin	DNA cross-linker	DNA cross-linker	25.2	uM	9566.011	0.4699	0.4475	2.3358
MCF 10F	NM	-	Oxaliplatin	DNA cross-linker	DNA cross-linker	126	uM	9566.011	0.1060	-0.2349	2.3358
MCF 10F	NM	-	Oxaliplatin	DNA cross-linker	DNA cross-linker	629	uM	9566.011	0.0045	-0.8028	2.3358
MCF12A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00161	uM	7873.011	1.0588	1.0557	2.0810
MCF12A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00805	uM	7873.011	1.0021	1.0020	2.0810
MCF12A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.0403	uM	7873.011	1.0403	1.0383	2.0810
MCF12A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.201	uM	7873.011	0.9624	0.9635	2.0810
MCF12A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	1.01	uM	7873.011	0.5167	0.4562	2.0810
MCF12A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	5.03	uM	7873.011	0.4141	0.3093	2.0810
MCF12A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	25.2	uM	7873.011	0.3356	0.1836	2.0810
MCF12A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	126	uM	7873.011	0.0169	-0.7187	2.0810
MCF12A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	629	uM	7873.011	0.0079	-0.8049	2.0810
MCF12A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00161	uM	10061.12	1.0442	1.0423	2.0669
MCF12A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00805	uM	10061.12	0.9789	0.9795	2.0669
MCF12A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.0403	uM	10061.12	0.9663	0.9671	2.0669
MCF12A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.201	uM	10061.12	0.8702	0.8699	2.0669

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)