Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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AU565 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 10880.155 | 0.9189 | 0.8918 | 1.5205 | |
AU565 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 10880.155 | 0.9189 | 0.8918 | 1.5205 | |
AU565 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 10880.155 | 0.9889 | 0.9853 | 1.5205 | |
AU565 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 10880.155 | 0.9889 | 0.9853 | 1.5205 | |
AU565 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 10880.155 | 0.9944 | 0.9926 | 1.5205 | |
AU565 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 10880.155 | 0.9944 | 0.9926 | 1.5205 | |
AU565 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 10880.155 | 1.0171 | 1.0225 | 1.5205 | |
AU565 | HER2amp | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 10880.155 | 1.0171 | 1.0225 | 1.5205 | |
AU565 | HER2amp | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 10880.155 | 1.0436 | 1.0570 | 1.5205 | |
AU565 | HER2amp | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 10880.155 | 1.0436 | 1.0570 | 1.5205 | |
AU565 | HER2amp | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 10880.155 | 0.9649 | 0.9535 | 1.5205 | |
AU565 | HER2amp | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 10880.155 | 0.9649 | 0.9535 | 1.5205 | |
AU565 | HER2amp | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 10880.155 | 1.0693 | 1.0901 | 1.5205 | |
AU565 | HER2amp | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 10880.155 | 1.0693 | 1.0901 | 1.5205 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.000171 | uM | 10581.146 | 0.9766 | 0.9597 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.000171 | uM | 10581.146 | 0.9766 | 0.9597 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.000853 | uM | 10581.146 | 0.9236 | 0.8681 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.000853 | uM | 10581.146 | 0.9236 | 0.8681 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.00427 | uM | 10581.146 | 0.9128 | 0.8493 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.00427 | uM | 10581.146 | 0.9128 | 0.8493 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0213 | uM | 10581.146 | 0.9765 | 0.9595 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0213 | uM | 10581.146 | 0.9765 | 0.9595 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.107 | uM | 10581.146 | 0.9696 | 0.9477 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.107 | uM | 10581.146 | 0.9696 | 0.9477 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.533 | uM | 10581.146 | 0.9332 | 0.8847 | 1.1650 |