Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.533 | uM | 10581.146 | 0.9332 | 0.8847 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 2.67 | uM | 10581.146 | 0.9472 | 0.9090 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 2.67 | uM | 10581.146 | 0.9472 | 0.9090 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 13.3 | uM | 10581.146 | 0.8369 | 0.7166 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 13.3 | uM | 10581.146 | 0.8369 | 0.7166 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 66.7 | uM | 10581.146 | 0.8413 | 0.7243 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 66.7 | uM | 10581.146 | 0.8413 | 0.7243 | 1.1650 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0000853 | uM | 11854.155 | 0.9448 | 0.9170 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0000853 | uM | 11854.155 | 0.9448 | 0.9170 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.000427 | uM | 11854.155 | 0.9479 | 0.9217 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.000427 | uM | 11854.155 | 0.9479 | 0.9217 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.00213 | uM | 11854.155 | 0.9241 | 0.8856 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.00213 | uM | 11854.155 | 0.9241 | 0.8856 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0107 | uM | 11854.155 | 0.9731 | 0.9597 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0107 | uM | 11854.155 | 0.9731 | 0.9597 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0533 | uM | 11854.155 | 0.9612 | 0.9417 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0533 | uM | 11854.155 | 0.9612 | 0.9417 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.267 | uM | 11854.155 | 0.9183 | 0.8768 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.267 | uM | 11854.155 | 0.9183 | 0.8768 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 1.33 | uM | 11854.155 | 0.9943 | 0.9914 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 1.33 | uM | 11854.155 | 0.9943 | 0.9914 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 6.67 | uM | 11854.155 | 0.8613 | 0.7890 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 6.67 | uM | 11854.155 | 0.8613 | 0.7890 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 33.3 | uM | 11854.155 | 0.9895 | 0.9844 | 1.3396 | |
BT-20 | TNBC | Basal A | PD184352 | MEK | MAPK | 33.3 | uM | 11854.155 | 0.9895 | 0.9844 | 1.3396 |