Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7496.093 | 0.8250 | 0.6428 | 0.9777 | |
| MDA-MB-157 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7496.093 | 0.5325 | 0.0497 | 0.9777 | |
| MDA-MB-157 | TNBC | Basal B | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7496.093 | 0.0367 | -0.9320 | 0.9777 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7506.093 | 1.0817 | 1.1789 | 0.9162 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7506.093 | 1.0520 | 1.1138 | 0.9162 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7506.093 | 1.0098 | 1.0213 | 0.9162 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7506.093 | 0.9761 | 0.9479 | 0.9162 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7506.093 | 1.0852 | 1.1867 | 0.9162 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7506.093 | 1.0566 | 1.1239 | 0.9162 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7506.093 | 1.0084 | 1.0182 | 0.9162 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7506.093 | 1.0065 | 1.0141 | 0.9162 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7506.093 | 0.0474 | -0.9283 | 0.9162 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.000171 | uM | 10472.1 | 1.0181 | 1.0574 | 0.6324 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.000853 | uM | 10472.1 | 0.9907 | 0.9708 | 0.6324 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.00427 | uM | 10472.1 | 0.9687 | 0.9021 | 0.6324 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.0213 | uM | 10472.1 | 0.9765 | 0.9262 | 0.6324 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.107 | uM | 10472.1 | 0.8606 | 0.5774 | 0.6324 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.533 | uM | 10472.1 | 0.8075 | 0.4262 | 0.6324 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 2.67 | uM | 10472.1 | 0.7864 | 0.3678 | 0.6324 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 13.3 | uM | 10472.1 | 0.4947 | -0.3429 | 0.6324 | |
| MDA-MB-361 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 66.7 | uM | 10472.1 | 0.0043 | -0.9996 | 0.6324 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7515.093 | 0.9846 | 0.9774 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7515.093 | 0.8720 | 0.8092 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7515.093 | 0.8746 | 0.8131 | 1.3657 | |
| MDA-MB-453 | TNBC | Luminal | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7515.093 | 0.8714 | 0.8082 | 1.3657 |