Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
LY2	HR+	Luminal	Oxaliplatin	DNA cross-linker	DNA cross-linker	629	uM	10264.011	0.0859	-0.6543	1.3983
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00161	uM	7867.011	1.0469	1.0391	2.3684
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00805	uM	7867.011	0.9916	0.9929	2.3684
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.0403	uM	7867.011	1.0807	1.0667	2.3684
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.201	uM	7867.011	1.0002	1.0002	2.3684
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	1.01	uM	7867.011	0.7410	0.7623	2.3684
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	5.03	uM	7867.011	0.4264	0.3954	2.3684
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	25.2	uM	7867.011	0.3829	0.3335	2.3684
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	126	uM	7867.011	0.1503	-0.1016	2.3684
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	629	uM	7867.011	0.0048	-0.7907	2.3684
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00161	uM	7870.011	1.0420	1.0391	2.1270
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00805	uM	7870.011	0.9402	0.9428	2.1270
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.0403	uM	7870.011	1.0196	1.0184	2.1270
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.201	uM	7870.011	0.9961	0.9963	2.1270
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	1.01	uM	7870.011	0.6674	0.6537	2.1270
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	5.03	uM	7870.011	0.4894	0.4293	2.1270
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	25.2	uM	7870.011	0.4538	0.3795	2.1270
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	126	uM	7870.011	0.1238	-0.2511	2.1270
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	629	uM	7870.011	0.0048	-0.8377	2.1270
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00161	uM	9551.011	1.0853	1.0599	2.7742
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.00805	uM	9551.011	0.9788	0.9846	2.7742
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.0403	uM	9551.011	1.0717	1.0506	2.7742
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	0.201	uM	9551.011	1.0661	1.0467	2.7742
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	1.01	uM	9551.011	0.9100	0.9332	2.7742
MCF 10A	NM	Basal B	Oxaliplatin	DNA cross-linker	DNA cross-linker	5.03	uM	9551.011	0.3998	0.4372	2.7742

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)