Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7834.075 | 0.0648 | -0.4847 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 10262.021 | 1.0839 | 1.2512 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 10262.021 | 1.0135 | 1.0398 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 10262.021 | 1.0513 | 1.1525 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 10262.021 | 1.0449 | 1.1333 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 10262.021 | 1.0275 | 1.0815 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 10262.021 | 0.8612 | 0.6059 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 10262.021 | 0.6796 | 0.1339 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 10262.021 | 0.2561 | -0.7298 | 0.6806 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 10262.021 | 0.0940 | -0.9380 | 0.6806 | |
| HCC1954 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9386.011 | 0.9987 | 0.9983 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9386.011 | 0.9199 | 0.8934 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9386.011 | 1.0034 | 1.0045 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9386.011 | 0.8691 | 0.8239 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9386.011 | 0.7181 | 0.6091 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9386.011 | 0.5705 | 0.3835 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9386.011 | 0.4738 | 0.2247 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9386.011 | 0.1336 | -0.4668 | 1.5229 | |
| HCC1954 | HER2amp | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9386.011 | 0.0535 | -0.7075 | 1.5229 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7841.075 | 0.9320 | 0.7558 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00806 | uM | 7841.075 | 1.0458 | 1.1725 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7841.075 | 0.9709 | 0.8936 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7841.075 | 0.9044 | 0.6608 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7841.075 | 0.8847 | 0.5947 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.04 | uM | 7841.075 | 0.8557 | 0.4993 | 0.5408 |