Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9376.011 | 1.0768 | 1.0958 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9376.011 | 1.0290 | 1.0365 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9376.011 | 1.0366 | 1.0460 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9376.011 | 0.8373 | 0.7875 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9376.011 | 0.5169 | 0.3175 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9376.011 | 0.3724 | 0.0707 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9376.011 | 0.0249 | -0.8065 | 1.5809 | |
| HCC1806 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9376.011 | 0.0131 | -0.8709 | 1.5809 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7832.011 | 0.9255 | 0.8952 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7832.011 | 0.9896 | 0.9856 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7832.011 | 0.9315 | 0.9037 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7832.011 | 0.8715 | 0.8177 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7832.011 | 0.6888 | 0.5433 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7832.011 | 0.6086 | 0.4161 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7832.011 | 0.4740 | 0.1903 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7832.011 | 0.1187 | -0.5453 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7832.011 | 0.0392 | -0.7894 | 1.4385 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7834.075 | 0.9984 | 0.9984 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00806 | uM | 7834.075 | 1.0767 | 1.0746 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7834.075 | 0.9948 | 0.9949 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7834.075 | 0.9280 | 0.9273 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7834.075 | 0.7767 | 0.7647 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.04 | uM | 7834.075 | 0.6952 | 0.6702 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7834.075 | 0.4986 | 0.4167 | 2.0182 | |
| HCC1937 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7834.075 | 0.1513 | -0.2155 | 2.0182 |