Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7804.011 | 0.9873 | 0.9894 | 2.4113 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7804.011 | 1.0305 | 1.0251 | 2.4113 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7804.011 | 0.9727 | 0.9772 | 2.4113 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7804.011 | 0.8328 | 0.8538 | 2.4113 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7804.011 | 0.5335 | 0.5412 | 2.4113 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7804.011 | 0.1429 | -0.1074 | 2.4113 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7804.011 | 0.0225 | -0.5851 | 2.4113 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7804.011 | 0.0052 | -0.7749 | 2.4113 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9024.075 | 0.9777 | 0.9845 | 2.8935 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00806 | uM | 9024.075 | 1.1189 | 1.0792 | 2.8935 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9024.075 | 1.0241 | 1.0165 | 2.8935 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9024.075 | 0.9399 | 0.9576 | 2.8935 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9024.075 | 0.6038 | 0.6800 | 2.8935 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.04 | uM | 9024.075 | 0.3992 | 0.4561 | 2.8935 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9024.075 | 0.0463 | -0.3084 | 2.8935 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9024.075 | 0.0169 | -0.5113 | 2.8935 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9024.075 | 0.0004 | -0.8710 | 2.8935 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 10261.011 | 1.0049 | 1.0040 | 2.4327 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 10261.011 | 1.0302 | 1.0246 | 2.4327 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 10261.011 | 0.9755 | 0.9797 | 2.4327 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 10261.011 | 0.8533 | 0.8737 | 2.4327 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 10261.011 | 0.5787 | 0.5973 | 2.4327 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 10261.011 | 0.3125 | 0.2398 | 2.4327 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 10261.011 | 0.3782 | 0.3410 | 2.4327 | |
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 10261.011 | 0.0449 | -0.4415 | 2.4327 |