Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7841.075 | 0.6023 | -0.2168 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7841.075 | 0.1677 | -0.9264 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7841.075 | 0.0217 | -0.9983 | 0.5408 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9402.011 | 1.0957 | 1.6190 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9402.011 | 0.9472 | 0.7039 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9402.011 | 0.9910 | 0.9471 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9402.011 | 1.0433 | 1.2666 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9402.011 | 0.9951 | 0.9709 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9402.011 | 0.9323 | 0.6263 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9402.011 | 0.6724 | -0.3800 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9402.011 | 0.3573 | -0.9041 | 0.3388 | |
| HCC202 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9402.011 | 0.0138 | -1.0000 | 0.3388 | |
| HCC2185 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7848.011 | 0.9984 | 0.9903 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7848.011 | 1.0197 | 1.1182 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7848.011 | 1.0195 | 1.1166 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7848.011 | 0.9735 | 0.8484 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7848.011 | 0.9697 | 0.8271 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7848.011 | 0.8777 | 0.3632 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7848.011 | 0.5594 | -0.6368 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7848.011 | 0.2109 | -0.9793 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7848.011 | 0.0076 | -1.0000 | 0.3405 | |
| HCC2185 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7849.011 | 1.0022 | 1.0081 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7849.011 | 0.9945 | 0.9798 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7849.011 | 0.9843 | 0.9428 | 0.5467 | |
| HCC2185 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7849.011 | 0.9868 | 0.9519 | 0.5467 |