Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 10261.011 | 0.0094 | -0.7067 | 2.4327 | |
| CAMA-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9210.011 | 1.0361 | 1.0767 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9210.011 | 0.9692 | 0.9348 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9210.011 | 0.9789 | 0.9553 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9210.011 | 0.9500 | 0.8942 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9210.011 | 0.8261 | 0.6336 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9210.011 | 0.7823 | 0.5419 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9210.011 | 0.6914 | 0.3529 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9210.011 | 0.1644 | -0.7046 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9210.011 | 0.0239 | -0.9617 | 0.9440 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7807.011 | 1.0276 | 1.0254 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7807.011 | 0.9883 | 0.9891 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7807.011 | 1.0487 | 1.0445 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7807.011 | 0.9775 | 0.9791 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7807.011 | 0.8449 | 0.8500 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7807.011 | 0.5132 | 0.4690 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7807.011 | 0.2831 | 0.1156 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7807.011 | 0.0294 | -0.6085 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7807.011 | 0.0079 | -0.7865 | 2.1620 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7808.011 | 1.2260 | 1.1749 | 2.4301 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7808.011 | 1.0328 | 1.0268 | 2.4301 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7808.011 | 1.0049 | 1.0040 | 2.4301 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7808.011 | 1.0216 | 1.0176 | 2.4301 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7808.011 | 0.6859 | 0.7126 | 2.4301 | |
| HBL-100 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7808.011 | 0.4003 | 0.3721 | 2.4301 |