Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7437.093 | 0.9609 | 0.8382 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7437.093 | 0.9356 | 0.7374 | 0.4731 | |
| HCC1419 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7437.093 | 0.6483 | -0.1998 | 0.4731 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.000171 | uM | 7442.1 | 0.9733 | 0.9393 | 0.8780 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.000853 | uM | 7442.1 | 0.9547 | 0.8972 | 0.8780 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.00427 | uM | 7442.1 | 0.9997 | 0.9994 | 0.8780 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.0213 | uM | 7442.1 | 0.9409 | 0.8660 | 0.8780 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.107 | uM | 7442.1 | 0.9496 | 0.8855 | 0.8780 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.533 | uM | 7442.1 | 0.9315 | 0.8447 | 0.8780 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 2.67 | uM | 7442.1 | 0.9149 | 0.8074 | 0.8780 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 13.3 | uM | 7442.1 | 0.6014 | 0.1207 | 0.8780 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 66.7 | uM | 7442.1 | 0.0162 | -0.9818 | 0.8780 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 10441.093 | 0.9618 | 0.9332 | 1.1458 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 10441.093 | 0.9337 | 0.8837 | 1.1458 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 10441.093 | 0.9848 | 0.9735 | 1.1458 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 10441.093 | 0.9693 | 0.9462 | 1.1458 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 10441.093 | 0.9760 | 0.9580 | 1.1458 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 10441.093 | 0.9200 | 0.8596 | 1.1458 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 10441.093 | 0.9673 | 0.9429 | 1.1458 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 10441.093 | 0.5551 | 0.1965 | 1.1458 | |
| HCC1428 | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 10441.093 | 0.0179 | -0.9402 | 1.1458 | |
| HCC1569 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 10442.093 | 0.9751 | 0.9703 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 10442.093 | 0.9706 | 0.9649 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 10442.093 | 0.9898 | 0.9879 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 10442.093 | 0.9591 | 0.9510 | 1.6861 |