Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 10442.093 | 0.9692 | 0.9632 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 10442.093 | 0.9296 | 0.9153 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 10442.093 | 0.9571 | 0.9486 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 10442.093 | 0.6099 | 0.4917 | 1.6861 | |
| HCC1569 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 10442.093 | 0.0201 | -0.8026 | 1.6861 | |
| HCC1806 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7451.093 | 0.9608 | 0.9638 | 2.1935 | |
| HCC1806 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7451.093 | 0.9315 | 0.9363 | 2.1935 | |
| HCC1806 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7451.093 | 0.9189 | 0.9243 | 2.1935 | |
| HCC1806 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7451.093 | 0.9269 | 0.9320 | 2.1935 | |
| HCC1806 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7451.093 | 0.9552 | 0.9586 | 2.1935 | |
| HCC1806 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7451.093 | 0.9297 | 0.9346 | 2.1935 | |
| HCC1806 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7451.093 | 0.9388 | 0.9433 | 2.1935 | |
| HCC1806 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7451.093 | 0.3429 | 0.2278 | 2.1935 | |
| HCC1806 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7451.093 | 0.0539 | -0.4720 | 2.1935 | |
| HCC1937 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7453.093 | 1.0743 | 1.0924 | 1.5872 | |
| HCC1937 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7453.093 | 1.0224 | 1.0281 | 1.5872 | |
| HCC1937 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7453.093 | 1.0014 | 1.0017 | 1.5872 | |
| HCC1937 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7453.093 | 1.0283 | 1.0355 | 1.5872 | |
| HCC1937 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7453.093 | 1.0648 | 1.0807 | 1.5872 | |
| HCC1937 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7453.093 | 1.0178 | 1.0224 | 1.5872 | |
| HCC1937 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7453.093 | 1.0283 | 1.0355 | 1.5872 | |
| HCC1937 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7453.093 | 0.7684 | 0.6941 | 1.5872 | |
| HCC1937 | TNBC | Basal A | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7453.093 | 0.2744 | -0.1145 | 1.5872 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7454.093 | 0.9328 | 0.8984 | 1.3347 | |
| HCC1954 | HER2amp | Basal A | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7454.093 | 0.8188 | 0.7219 | 1.3347 |